Difference Between Antigens and Antibodies
By Marc Gordon - June 12, 2022

Antigens and antibodies play essential but separate functions in sickness and disease. One seeks to wreck our health, while the other struggles to keep it safe. Antigens may make you sick, and antibodies are the body’s defense mechanism against them. We’ve heard a lot about antigens and antibodies since COVID-19 took the world by storm. Have you ever wondered what they are and how they differ from one another? You’ve come to the perfect location if you have questions and need answers! Please continue reading to learn more about antigens and antibodies and how they affect your health.

Table Summary

They are also called ImmunogensThey are also called Immunoglobulins
They are usually lipid. Antigens can be Protein, Carbohydrates, or Nucleic AcidAll antibodies are protein
Antigens can trigger allergic responses or even disease.Protects against the effects of the antigen either by lysis or immobilization of the particle
Antigens originate from outside the body.The body always produces antibodies.


Antigens, also known as immunogens, are poisons or molecules found in our blood that drive our bodies to fight them because they are alien. Antigens are bacteria or viruses, but they may also be strange substances harmful to one’s health.

Immunoglobulin is another name for antibody (Ab) (Ig). Plasma cells create large Y-shaped blood proteins, and they attach to and infiltrate foreign particles. Antigens are foreign pathogens that penetrate the body and have the ability to trigger an immune response.

Antigens VS Antibodies

Antigens usually are classified as self or non-self. Self-antigens develop in the body, much like cancer cells. Non-self-antigens are foreign substances that enter the body. They cause your immune system to make more antibodies, distinguishing between antigen and antibody. Antibodies come in five main varieties, each of which is unique. IgA, IgE, IgG, IgM, and IgD are several types of antibodies.